Once access has been gained, Rad51 polymerizes on the DNA strand to form what is called a presynaptic filament, which is a right-handed helical filament containing six Rad51 molecules and 18 ...

A team of researchers has used advanced DNA sequencing to develop the most comprehensive atlas yet of genetic change through generations, laying the foundations for new insights into the roots of ...

TREs occur when sections of a DNA strand are repeated two or more times, and the likelihood of those repeats causing errors in gene function increases each time. In 2020, Yuen discovered that TREs ...

Genetic information is passed from one generation ... Base pairs on a section of DNA The order of the bases along a strand of DNA is a code – a code for making proteins. These proteins in ...

This direct observation sheds light on the fundamental mechanisms that allow cells to faithfully duplicate their genetic ...

Base-editing technologies along with AAV engineering not only help reduce costs but can also accelerate preclinical ...

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

Chromatin regulators help moderate gene expression, cell division, and DNA damage repair by unwinding ... to track numerous adjacent segments as the strand folds and unfolds.