University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their ...

A protein called PriC allows DNA replication to proceed in Escherichia coli when the complex that usually initiates this process is compromised.

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

By Livia Albeck-Ripka Reporting from Los Angeles Los Angeles County will retest about 4,000 DNA samples connected to criminal cases after discovering that it had been using potentially defective ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues ...

The findings visualize for the first time a molecular complex—called CTF18-RFC in humans and Ctf18-RFC in yeast—that loads a "clamp" onto DNA to keep parts of the replication machinery from ...

However, during recombinant AAV production, nonhomologous recombination between the AAV vector and packaging DNA can lead to the formation of rcAAVs. These replication-competent vectors ...

Diagram of DNA replication. Process by which a double stranded... The graphic shows the duplication of a DNA chain on a gray background. Vector image The graphic shows the duplication process of a DNA ...

Scientific model DNA and RNA transcription and translation... Scientific biological model DNA and RNA transcription and translation vector illustration isolated on white background. Spiral genetic ...

Faithful DNA replication is critical for genomic stability maintenance ... lentiviral particles were produced in HEK 293T by transfecting the pCSII-EF-MCS empty vector (as a control), ...

These enzymes are essential to DNA replication and usually work in pairs ... DNA Polymerase enzyme syntheses labeled educational vector illustration. Image Credit: VectorMine / Shutterstock ...