Scientists have uncovered a critical role for rapid DNA repair in maintaining genome stability. A new study reveals that ...

Freeze–thaw cycles in an icy pond could let an enzyme copy RNA double helices indefinitely — suggesting one way in which ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

POLG mutations impair mitochondrial DNA replication and cause diverse mitochondrial diseases. Here, the authors show that structural differences in the POLγB subunit between humans and mice ...

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through ...

We report the design and construction of a nanometer-sized tetrahedron from a single strand of DNA that is 286 nucleotides long ... of the tetrahedron can be easily scaled up through in vivo ...

The exonuclease-amplified assay can detect target DNA at concentrations as low as 10 pM when performed at 37 °C, which represents a significant improvement over the equivalent molecular beacon alone.