Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have ...

End capping of oligonucleotides is crucial for enhancing their stability and therapeutic efficacy by resisting 3’ exonuclease degradation, yet the underlying mechanisms remain elusive.

Saur, Lesage et al. report that RNA:DNA hybrids arise at double-strand breaks in transcribed genes, independently of de novo recruitment of RNA polymerase II/III, as a result of DSB-induced ...

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