4 The term “cis” refers to interactions between regulatory elements and oncogenes both residing within the same ecDNA molecule ... of thousands of DNA base pairs, offers the means to ...

Next-generation DNA sequencing has started ... called the HeliScope single-molecule sequencer. To prepare a sample, DNA is fragmented into 100–200-base-pair pieces, and then adaptors of known ...

It uses sophisticated imaging techniques and precise microfluidics control to stretch curly DNA into a straight line. Immobilizing the molecule ... individual base pairs, these methods enable ...

and a nitrogen-containing base. They were first identified in the late 1860s by Swiss chemist Friedrich Miescher. As the years marched on, other scientists, including Phoebus Levene and Erwin Chargaff ...

Barber Faculty of Science study biophysics at the single-molecule ... this DNA-based system consists of two components: the fish and the hook. Using complementary DNA base-pair interactions ...

Since Dr. Nadrian Seeman introduced the concept of DNA nanotechnology ... single quantum emitters (10.1021/acsaom.4c00356). These efforts have created unidirectional transmitting optical nanoantennas ...

While MethylCap-seq does not offer base-pair ... DNA libraries were created by ChIPmentation method (Schmidl et al., 2015). Briefly, methylated DNA fragment-bound beads were resuspended in 30 μl of ...

A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we ...