News

Hidden architecture: Researchers identify new molecular structure at center of chromosomes
Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...
Brown University3d
Ancient Mediterranean DNA confirms old truths: People contain multitudes
An ancient DNA study co-authored by Brown archaeologist Peter van Dommelen illustrates the complexity of human migration and ...
Findings uncover new mechanism linking cohesin complex to gene regulation
Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...
Nature4d
Rare ‘ambidextrous’ protein breaks rules of handedness
Most proteins are left-handed, but scientists have found an ancient molecule that works in both mirror-image forms.
C&EN5d
Single-Molecule Manipulation of the Duplex Formation and Dissociation at the G-Quadruplex/i-Motif Site in the DNA Nanostructure
The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acsnano.5b03413. DNA sequences, additional experiments, and additional AFM images (PDF) Movie 2.
C&EN6d
Small Molecule Benzothiophene with In Vivo Efficacy in a Mouse Model of Drug-Resistant Enterococcus faecium Infection
Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenço Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University─New Jersey Medical School, Newark 07103, ...
eLife6d
Structural mechanism of strand exchange by the RAD51 filament
This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...