Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

Carina Dennis of the science journal Nature explains the significance and consequences of Watson and Crick's landmark 1953 discovery. DNA is, in every sense, a modern icon. For decades, it has ...

We identified additional protein domains predicted to be essential for virus genome replication. Analysis of the presence ... Structural comparison of the DNA-bound LF/PAD of the Escherichia coli DNAP ...

We could use them to make new, never-before-seen proteins ... letting them fit into a DNA helix without disrupting its structure. Consequently, enzymes could read and copy synthetic nucleotides ...

The viral DNA ... the capsid is made of 235 copies each of two proteins, and the other nine virion proteins have copy numbers from two to 72. In total, the virion is made up of 645 protein pieces that ...

For the proper assembly of the immature capsid, the functional CA protein must present the ... V-markers found in p24 on the capsid structure, assembly, molecule-binding, and other functions in the ...

The virus is then put together with the capsid proteins surrounding the DNA. If the virus ... The basic structure of a host cell is shown in figure 2. RNA viruses must carry the genes for the proteins ...