The team discovered that in comparison with young neurons, old neurons displayed hallmarks of molecular stress, such as ...

CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China, Department of Biomedical ...

The authors advance this technique by integrating peptide ligation technology and nanobody-based antibody mimetics - cost-effective and scalable alternatives to conventional antibodies - into a ...

YB‐1 is a DNA/RNA‐binding nucleocytoplasmic shuttling protein whose regulatory effect on many DNA‐ and RNA‐dependent events is determined by its localization in the cell. Distribution of YB‐1 between ...

The modified PNA recognizes and binds to the complementary DNA strand in accordance with Watson−Crick recognition rules. However, unlike polypyrimidine PNA which binds to DNA in 2:1 stoichiometry, the ...

In this extraneous context, TBX3 adopts new functions: Instead of binding the DNA as a classic transcription factor, it employs short, conserved motifs on its surface to stick to other protein ...

Department of Molecular Biology, Kyushu University Graduate School of Pharmaceutical Sciences, Fukuoka, Japan ...

Two proteins, TRF2 and RAP1, work together to block a repair process that would otherwise treat the natural ends of chromosomes as broken DNA and try to fix them. Formation of the TRF2–RAP1 ...