Traditional storage solutions are reaching their limits in light of the steadily increasing volume of data generated worldwide. In the BIOSYNTH project, three Fraunhofer institutes are developing a ...

The only remaining autonomous 'jumping gene' can only attach to, and stitch a copy of itself into, DNA when it builds up into large clusters and only as cells divide.

Viruses are known to use the genetic machinery of the human cells they invade to make copies of themselves. As part of the ...

In 2015, a 7.8 earthquake hit Nepal, killing nearly 9,000 and injuring thousands. The earthquake resulted in losses exceeding ...

A human genome has 3.2 billion base pairs, or sequences formed by the four nucleotides [adenine (A), cytosine (C), guanine (G) and thymine (T)]. These pairs are organised into long molecules of DNA ...

In this study, we demonstrated that pharmacological inhibiting thymine DNA glycosylase (TDG), a multifunctional DNA modifying enzyme with essential roles in DNA base excision repair (BER), ...

Thymine DNA glycosylase (TDG) is a multifaceted enzyme involved in DNA base excision repair (BER), transcriptional regulation, and DNA demethylation, playing critical roles in both embryonic ...

Thymine DNA glycosylase (TDG) is a DNA glycosylase involved in base excision repair (BER) with a specialized role in the regulation of transcription through the maintenance of 5′-CpG-3′ sites via ...