This overabundance of cytokines can lead to inflammation ... Discovery that describes their initial findings. The proteins are similar in structure, and act in a similar way, to other proteins ...

This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal. A team of MIT researchers has developed specialized proteins, similar in structure to ...

Figure 1: The structure and function of SOCS proteins ... inflammation-associated tumorigenesis. The use of SOCS proteins to suppress cytokine signalling could be a useful therapy for the ...

They have obtained the first structure of p38α being activated by another regulatory protein kinase – MKK6 – opening up new directions to develop drugs to stop cytokine storms. The final ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

For example, structure-modified superkines with increased ... chimeric antibody-cytokine fusion proteins or infusion of anti-cytokines in association with cytokines are being investigated to ...

The major cell types and cytokine ... is a fusion protein made up of two recombinant p75 soluble TNF receptors fused with the Fc portion of human IgG1. The dimeric structure of etanercept makes ...

rather than what's actually being produced," says Fred Finkelman of the University of Cincinnati. So many scientists measure cytokine protein directly instead. Using as their key reagents an ...

Tong and Cai, in collaboration with chemical engineering and materials science and engineering graduate students, have developed an innovative approach to employ cytokine proteins as a potential ...

Psoriasis causes your body to make new skin cells too quickly. These cells tend to pile up and form spots, bumps, and thick scaly patches called plaques that can be uncomfortable. Scientists think ...