The platform's screening capabilities include genome-wide and targeted CRISPR libraries for knockout (CRISPR KO), inhibition ...

IRBM, an integrated Contract Research Organization (CRO) specializing in preclinical drug discovery, has established a ...

Full details of the work are published in a new Cell Stem Cell paper titled, “Self-organization of embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming.” ...

Deanna earned their PhD in cellular biology from McGill University in 2020 and has a professional background in medical writing. They are an associate science editor at The Scientist. View Full ...

Additionally, we used CRISPRa to overexpress insect developmental genes which, which results in complete lethality. We first did this as a proof of concept in flies, and we showed that this works in ...