The high mobility group AT-hook 2 (HMGA2) has emerged as a novel chromatin architectural regulator, its specific role in TNBC metastasis requires further investigation. Methods: We analyzed the ...

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This research was supported by funding from the Singapore Ministry of Education (RG145/18, RG93/22, and RT3/22 to W.Z.; MOE-MOET32020-0001 to A.L. and W.Z.), Ministry of Healthy [Healthy Longevity ...

On May 6, Florida Gov. Ron DeSantis said he would sign (SB 56), which would prohibit "geoengineering and weather modification activities" in Florida, including cloud seeding. It's the process of ...

In this study, we developed a convenient histone modification detection system by combining a chromatin immunoprecipitation (ChIP) and bioluminescence resonance energy transfer (BRET)-based ...

Conclusions: CTU2 may serve as a valuable prognostic and immunotherapeutic biomarker across multiple cancer types, providing new insights into tumor treatment strategies and immune evasion from the ...

presents important findings on the metabolism-independent role of nuclear IDH1 in chromatin regulation during erythropoiesis ... is the key enzyme that can modulate cellular metabolism, epigenetic ...

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing ...

FMC-220 is designed to address the potency and durability challenges seen with non-covalent approaches targeting the structurally destabilized p53 Y220C mutant. Preclinical studies showed FMC-220 ...

2024]). Another critically important protected sphere is a parent’s right to simultaneously prosecute an appeal and file a modification petition. Family Court must not condition a parent’s ...