In a perspective, Northwestern Engineering’s Chad Mirkin and Milan Mrksich argue that structural precision drives therapeutic ...

SNAs are a globular form of DNA that can easily enter cells and bind to targets. More effective than linear DNA of the same sequence, SNAs have demonstrated significant potential in gene regulation, ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Ingrida Domarkienė, a geneticist at Vilnius University in Lithuania, discusses the exciting developments made possible by ...

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

New research challenges the view that proteins are the only key to evolution, highlighting the importance of lipids.

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

Researchers have produced the most detailed image to date of a bacteriophage -- phage for short -- that has allowed them to see for the first time the structural makeup of the part of the phage that ...