Merck's ( NYSE: MRK) experimental antibody drug conjugate zilovertamab vedotin, in combination with standard of care, ...

Ankyra Therapeutics is a biotech developing anchored immunotherapies aimed at enhancing the therapeutic window of ...

Find more information on the Altmetric Attention Score and how the score is calculated. G protein-coupled receptors (GPCRs) transduce information encoded by external stimuli into an appropriate cell ...

Subgroup analysis by drug class showed a pooled mean change of 5.70% (95% CI 1.61 to 9.78) for anti-TNF biologics, compared with 0.16% (95% CI −2.61 to 2.93) for non-TNF biologics. This suggests the ...

TWEAK (tumour necrosis factor (TNF)-like weak inducer of apoptosis) is a member of the TNF superfamily of structurally related cytokines. It is present on the cell surface but a soluble form can ...

Weak Hero Class 2 has taken raw intensity and compelling characters to the next level. Each confrontation between the characters has left the fans breathless, as Si-eun’s new school has also thrown ...

Ploegh, September 21, 2021 (sent for review September 1, 2021; reviewed by Pamela J. Bjorkman and Peter Cresswell) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of ...

Assembly of antigen-specific T cell and B cell receptors occurs through ... In addition to adaptive T helper 2 (Th2) cells, group 2 innate lymphoid cells (ILC2s) contribute to type 2 immune responses ...

Notably, IBI302—a novel global first-in-class bispecific molecule (anti-VEGF/anti-complement) —recently reported Phase 2 data showing that its high-dose cohorts met the primary endpoint. The treatment ...

Biologics are a novel class of agents that are ... IL-15, IL-17 and receptor activator of nuclear factor κB ligand form a complex cytokine network with IL-1 and tumor necrosis factor that ...