A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Because cell cycling determines effector function, pathogenic events in CD and UC may depend on cell cycle changes unique to each condition. Methods: Cell cycle kinetics, cycle regulatory molecule ...

During interphase, the chromosomes of animal cells are organized into regions with high intra-chromosomal interactions, which are known as topologically associating domains (TADs), and regions of ...

School of Food and Biological Engineering, Hefei University of Technology, Hefei 230009, People’s Republic of China Anhui Province Key Laboratory of Functional Compound Seasoning, Anhui Qiangwang ...

These genes are essential for cell cycle regulation, including processes such as ... is a microtubule-associated motor protein involved in the regulation of chromosome condensation and separation ...

In this review, we discuss how the molecular organization of the four modules allows a dynamic integration of kinetochore–microtubule attachment with the prevention of chromosome segregation errors ...

“Will the cycle eventually catch up to patients who have gone through CAR T-cell therapy? Does innate immune dysfunction disappear with CAR T or BiTE? Interferon responses and long-term ...

Institute of Human Genetics, University of Cologne, 50931 Cologne, Germany Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital, University of Cologne, 50931 ...

We demonstrate that mTORC1 inhibition by rapamycin preserves the progenitor pool by reinforcing quiescence and preventing alternative cell cycle progression for centriole amplification. Overexpressing ...

Unseen and ongoing, thousands of times every second: to keep a complex organism like humans alive, an immense number of new cells must be continuously produced. Up close, each of these cell ...