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Study reveals intricate molecular detail of human DNA repair process
A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...
Nature3d
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
Figure 2: Binding of B7-H1 to CTLA4, ICOS and CD28. We measured the amounts of IL-2, IL-4, IFN-γ and IL-10 produced by T cells after stimulation with B7-H1Ig, B7-1 immunoglobulin (B7-1Ig ...
gut.bmj4d
Divergent cell cycle kinetics underlie the distinct functional capacity of mucosal T cells in Crohn’s disease and ulcerative colitis
Because cell cycling determines effector function, pathogenic events in CD and UC may depend on cell cycle changes unique to each condition. Methods: Cell cycle kinetics, cycle regulatory molecule ...