Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves.

Histone modifications have been shown to play a role in chromatin packing and accessibility, nucleosome mobility, gene expression, and chromosome arrangement. In this review, we critically evaluate ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Department of Physics, North Carolina State University, Raleigh, North Carolina 27607, United States Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27607, ...

Department of Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China Introduction: The recombinant human p53 adenovirus (Ad-p53) offers a ...

It wasn’t until moving to the French Alps when I was 19 that I appreciated how much easier it is to pack ski gear when you use a thorough packing list to ensure smooth travels. Here is ...

Here we assessed the interplay between OCT4 and SOX2 in controlling chromatin accessibility of mouse embryonic stem cells. We found that OCT4 and SOX2 operate in a largely independent manner even at ...

Cells meet this challenge by combining their DNA molecules with proteins to form a compact and highly organized structure called chromatin. Packaging DNA into chromatin also reduces damage to it. But ...