Complex traits are influenced by genes and the environment, but especially the latter is difficult to pin down. This important study uses C. elegans to demonstrate that non-genetic differences in gene ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Regular consumption of sugar-sweetened beverages is associated with lower sperm count, motility, and increased DNA damage, ...

Once a DNA lesion is repaired, DDR foci are disassembled. This is probably due to the action of both chromatin remodelling machines and the dephosphorylation of γH2AX by dedicated phosphatases 24.

They noticed unapproved changes had been made to the rear attenuator, a safety device designed to absorb and reduce the force of impacts, and the assumption was the modifications would have given ...

Also, breeders may be unable to determine which genetic change led to a new trait. Genetic modification accelerates this process by using scientific techniques that give the plant the desired trait.