The modification state helps determine whether the nucleosome is an appropriate substrate for a remodeler complex (Saha et al., 2006), as discussed later in this article. Chromatin structure is ...
A surprising mix of inherited and de novo mutations in 60 genes contribute to 10 percent of CHD cases. Many of these same ...
Histones not only keep DNA organized, but also help regulate gene expression. How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell ...
Chromatin, the mix of DNA and protein that ... occurring chemical changes to the protein called post-translational modifications, or PTMs. By changing the physical and chemical structures of ...
A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind ...
Chromatin is the physiological state of the genome ... A major, but not exclusive focus of our lab is the analysis of histones, their variants, post-translational modifications and proteoforms.
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