Chromatin is a flexibly joined chain of nucleosomes ... showing that CODANIN-1 utilizes histone H3-mimic helices and B-domains to sequester ASF1A, thereby inhibiting ASF1 function.
A research team led by Prof. Cao Xiaofeng at the Institute of Genetics and Developmental Biology (IGDB) of the Chinese ...
Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...
Figure 1: Dnmt1 actively represses transcription using sequences that overlap the HRX repression domain. Figure 2: Dnmt1 686–812 represses transcription in a TSA-sensitive manner and has the ...
Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...
The Fellows of the AACR Academy have elected Elaine V. Fuchs, PhD, FAACR, as their next President. She will assume the ...
Dianna Gunn built her first WordPress website in 2008. Since then, she's poured thousands of hours into understanding how websites and online businesses work. She's shared what she's learned on ...
Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...
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The measles virus attacks long-lived immune cells, reducing antibody-mediated protection from other infectious diseases and casting a long shadow of childhood mortality.