"GPCRs, specifically β2AR, are critical for these functions of microglia cells. Equipped with our chimera receptor of β2AR, the microglia cells replicated the process of driving inflammation in ...

Nine (27%) patients had prior anti-BCMA CAR T-cell therapy. Fig 1. Flow diagram. BCMA, B-cell maturation antigen; CAR, chimeric antigen receptor; GPRC5D, G protein–coupled receptor, class C group 5 ...

Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes through four G protein-coupled receptor (GPCR) subtypes: EP1–EP4. While the ...