This allows other cell-signalling proteins to influence NF-κB function and therefore serves as a mechanism to integrate their activities with the NF-κB and IKK pathway. NF-κB subunits can also ...

Cellular signaling is an elaborate, dynamic, and interactive system of inter- and intracellular communication, responsible for governing and coordinating activities, from the basic to the complex.

which includes cellular signaling pathways and downstream targets, cell differentiation and organismal development, responses to cell stress and nutritional requirements, and programmed cell death.

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

How you communicate with others says a lot about you. You probably already knew that, but did you also know that it can tell you which cell signaling pathway you are? Lab safety rules dictate that one ...

How do these molecules activate signaling pathways in their target cells? They bind to cell-surface proteins of the seven-helix-G protein-coupled receptors (GPCRs). These in turn activate either ...

Lipids in cell membranes regulate the activity of a cancer-linked protein, cell biologists at RIKEN have discovered. This ...

A team of Chinese researchers led by Prof. WANG Likun from the Institute of Biophysics of the Chinese Academy of Sciences has provided new insights into metabolic disease mechanisms and potential ...

Previous work by the team had shown that the NOTCH signaling pathway played a central role ... is involved from the very start of the CD8 + T cell differentiation period, which lasts around ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

This study fills a crucial gap in our understanding of blood cell formation from human pluripotent stem cells (hPSCs). Genome-wide comparisons of hPSC-derived blood progenitor cells with in vivo blood ...