ACVR2A downregulation disrupts the TCF7/c-JUN pathway, impairing trophoblast invasion and proliferation in pre-eclampsia, revealing a genetic susceptibility-associated mechanism of placental ...

Aggressive breast cancer can become unresponsive to monoclonal antibody treatment, but targeting tumor-resident bacteria may extend its effectiveness.

Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes ...

Discover 12 scientifically-backed breast cancer fighting foods. Learn which nutrients protect cells, reduce inflammation, and ...

This study presents an important finding on the role of GATA4 in aging and OA-associated cartilage pathology. The evidence supporting the conclusions is compelling, with rigorous in vitro and in vivo ...

Phosphoinositide signaling pathways have been implicated in the metabolic alterations associated with various human diseases, including breast cancer. The phosphatidylinositol-5-phosphate 4-kinase ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly ...

I am investigating how plants detect the presence of potential pathogens, and how this recognition triggers a complex network of signaling pathways inside the plant cell.”, said Zhang. “I’ve been ...

But sometimes, things go wrong... Miscommunication between cells can interfere with crucial signaling processes. By understanding these pathways and pinpointing the source of miscommunication, we can ...