Anaplastic large cell lymphoma (ALCL ... epigenetic factors are among the most common genetic changes in tumours. Inhibitors that target epigenetic enzymes are already in clinical use and show ...

To investigate the possible antitumor effects of DDR inhibitors in DSRCT and other solid tumors occurring in younger patients, a screen using a 26-agent panel relevant to the DDR pathway and four ...

A new era of cell therapy has well and truly arrived with the iPSC field setting a trailblazing fire with its potential to develop fully scalable, off-the-shelf cell lines reducing the cost of ...

Because iPSCs can be multiplied almost limitlessly, you can overcome the challenge of scale that MSC-based therapies have faced over the last decade. So, how do you obtain MSCs? These cells are ...

Ten years have elapsed since the government gave its full policy support for the research field of regenerative medicine centered on iPS cells. In 2012, Shinya Yamanaka of Kyoto University was ...

If a Splinter Cell remake fell in the woods, would over the top industry secrecy and NDAs even allow us to hear it? That's the million dollar question literally no one is asking, because who phrases ...

Sensorineural hearing loss happens most often from damage to the hair cells in the inner ear. Other causes include damage to the nerve for hearing, called the auditory nerve, or the brain.

We found that toyocamycin (TOY) induced rapid reorganization of the actin cytoskeleton in A549 cells, causing them to become circular, irregular, or ellipsoidal in shape. Mapping of the dynamic ...