A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.

But while the standard somatic cell modification makes changes to a person’s genome in ways that cannot be passed down to offspring, germline modification does. And excluding issues of efficacy ...

RNA comes in several variants which all have specialized roles in cells. Modifications to the chemical structure ... who’s interested … can be part of” regardless of their background. At the center, ...

RNA modification marks are often deregulated in cancer cells Methyladenosine marks on ... explaining the background to the work. The study focused on the nuclear enriched abundant transcript ...

The research paper "In vivo Hematopoietic Stem Cell Modification by mRNA Delivery" discusses a groundbreaking approach to altering hematopoietic stem cells within the body. These stem cells are ...

That "modification" might change your experience quite a bit. In our cells, molecules called phosphate groups are constantly attaching to—or detaching from—proteins. These "post-translational ...

SUMOylation is a post-transcriptional modification involved in various cellular processes such as transcriptional regulation, apoptosis, protein stability, and cell cycle progression. Humans have ...

So, PTM creates an additional delicate level of regulation of protein function, which allows to respond more actively to the changes, occurring in the cells. Modifications take place in the ...

Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This tool, a mintbody or modification-specific intracellular antibody, will ...

This research has future implications and can be used to monitor the dynamics of histone modifications and genome integrity in single living cells without disturbing cellular functions. Genomic ...