New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

An international research team has provided a detailed insight into how the spatial organization of genetic material is established in the cell nucleus of early embryos within the first hours after ...

After earning a dual MD–PhD from the University of Maryland, Porter used his background in muscle cell biology to investigate heart development at Yale. It wasn’t until his move to Rochester, however, ...

Mitochondrial homeostasis is crucial for the maintenance of cellular equilibrium. In neurons, which are non-regenerative cells, mitochondrial dysfunction ...

Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...