Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular ...

What the bacteria do next would hold the key. It turned out that the CRISPR sequences team up with certain proteins (Cas9) to form a pair of molecular scissors that cut away and destroy the virus DNA, ...

A pair of privately-held developers of editing-based therapies have some successes to show for their recent efforts to ...

That is a key feature that has made Cas9 such a powerful tool ... mostly occurring in bacteria-infecting viruses. Sequences within each gene's repetitive region—its TIGR arrays—encode ...

In contrast, the CRISPR/Cas9 size range is 4000-5000 base pairs ... which is an important marker in patients infected with hepatitis B virus. In particular, HBeAG-negative people who have been ...

DNA segments that can move from one part of the genome to another -- are key to bacterial evolution and the development of antibiotic resistance. Researchers have discovered a new mechanism these ...

Researchers have identified an ancient RNA-guided system that can target DNA, potentially expanding the genome-editing toolbox.

Hepatitis B virus (HBV) infection remains an urgent global health concern, affecting hundreds of millions of people and significantly heightening the risk ...

Genetically modified pigs with human-compatible organs offer a potential solution to the organ shortage crisis, with ongoing research focusing on modifying pig organs to reduce rejection and improve ...