Laboratory of Human Genetics & Therapeutics, Smart Health Initiative, Division of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Molecular logic gates, as biomolecule-based computational systems, are highly suitable ...

We demonstrate that these ancient forms were much more flexible in their guide RNA and protospacer-adjacent motif requirements compared with modern-day Cas9 enzymes. Furthermore, anCas portrays a ...

Although various methods of trait improvements in crops are available and are being used, clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9 (CRISPR/Cas9) ...

The development of precise and efficient delivery systems is pivotal for advancing CRISPR/Cas9 gene-editing technologies, particularly for therapeutic applications. Engineered metal–organic frameworks ...

So, she began the “All Boys” project and used CRISPR-Cas9 technology to alter sex ratios ... The cut in the second strand targeted a short DNA sequence, the protospacer-adjacent motif site, to ...

Deanna earned their PhD in cellular biology from McGill University in 2020 and has a professional background in medical writing. They are an associate science editor at The Scientist. View Full ...

Attempts by Cas1-Cas2 to complete protospacer insertion by the integration of the second ... were dialyzed against 20 mM Tris-HCl (pH 7.5), 150 mM KCl (Cas1, Csn2, and Cas9) or 500 mM KCl (Cas2), 1 mM ...