Using an inexpensive electrode coated with DNA, MIT researchers have designed disposable diagnostics that could be adapted to ...

MIT’s CRISPR sensor detects cancer and HIV for 50 cents and stays effective for two months without refrigeration.

When fused to an enzyme, Cas9 and Cas12 can make targeted chemical changes to DNA at locations determined by the gRNA sequence. The team chose Cas12 because of its innate ability to process an RNA ...

MIT has developed a DNA sensor that can detect HPV and HIV infections through voltage changes. The sensor is durable and ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence.

CRISPR-Cas systems protect bacteria by capturing viral DNA as genetic memories, known as spacers. Here, authors used deep mutational scanning to identify Cas1 and Cas2 variants that enhance spacer ...

Immunotherapy has emerged as one of the most promising therapeutic strategies in cancer. The clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 (CRISPR-Cas9) system ...