At the upcoming annual meeting of the American Society of Gene and Cell Therapy, scientists from Huidagene Therapeutics will share an update on the development of their CRISPR-high-fidelity(hf ...

PL BioScience, a German life science company specializing in the production and development of human platelet lysate (HPL) for cell expansion, reported the first-time production of an artificial ...

Cas12 家族核酸酶（如 Cas12a、Cas12b 和 Cas12f）能有效克服这些限制。Cas12a 和 Cas12b 可识别富含 T 的 PAM 序列，扩大了可编辑位点范围；Cas12f 能特异性切割单链 DNA（ssDNA），且无需特定 PAM 序列 ...

First, direct repeat sequences, based on the CRISPR variant the user selected, are appended to either the 3′ of each of the spacer sequences provided by the user for the Cas12 variants or the 5' of ...

To uncover synthetic lethality or viability with metabolic enzymes, that might only be observable under growth conditions other than standard high glucose medium, we performed the Cas12-SLCxEnzymes ...

引起广泛关49图库免费的资料港澳大全注的CRISPR编辑技术，用到的蛋白通常为Cas9和Cas12。不过，这些蛋白比较笨重，“拖家带口”。TnpB被认为是Cas12的祖先，它更古老，也更紧凑，是有巨大潜力 ...

引起广泛关注的CRISPR编辑技术，用到的蛋白通常为Cas9和Cas12。不过，这些蛋白比较笨重，“拖家带口”。TnpB被认为是Cas12的祖先，它更古老，也更紧凑，是有巨大潜力的微型基因编辑工具。