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An animated 3D maximum projection through 60 µm of thymus tissue (related to Fig. 8d) from a representative FoxN1Cre R26Confetti LPOFGF21 mouse at 6 months of age. Blue, CFP; yellow, YFP; red, RFP.
We discovered the function of the thymus and made key findings on the function of the two main subsets of lymphocytes, T cells and B cells. This was the fundamental basis for modern immunology.
He subsequently developed dyspnea on exertion. Diagnosis. Carcinoid tumor of midgut origin with large segment 3 liver metastasis. Carcinoid syndrome and carcinoid heart disease. Management.
CAR T cells are made by genetically altering a patient’s own T cells, which are unique cells of the immune system that develop in the thymus, to express specific antigen receptors (receptors ...
Researchers have created a new kind of nanoparticle that could make ultrasound-based cancer treatments more effective and safer, while also helping prevent tumors from coming back. The study ...
As the thymus ages, the walls of these structures collapse. Upon thymic regrowth, the walls are rebuilt. Experiments in mouse models showed that an increase in FGF21 could delay thymic atrophy.
Speaking to The Times U.K. in a new interview, The Crown star discussed her experience with VIPoma (vasoactive intestinal peptide-secreting tumor), a rare neuroendocrine tumor of the pancreas that ...
Among patients with mismatch repair–deficient (dMMR), locally advanced rectal cancer, neoadjuvant checkpoint blockade eliminated the need for surgery in a high proportion of patients. Whether ...
Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele ...
Crinetics' lead development candidate, paltusotine, is the first investigational once-daily, oral, selective somatostatin receptor type 2 (SST2) nonpeptide agonist that is in clinical development for ...
Erin McBride, a brain tumor survivor, will run the Boston Marathon to celebrate life and thank the Mass General Hospital team that saved her. McBride’s brain tumor was partially removed while ...