To produce cannabinoids in yeast (Saccharomyces cerevisiae), UC Berkeley synthetic biologists first engineered yeast's native mevalonate pathway to provide a high flux of geranyl pyrophosphate ...

MIRA Pharmaceuticals signs letter of intent to acquire SKNY Pharmaceuticals, adding SKNY-1, a preclinical drug for weight ...

Chemically modifying a synthetic cannabinoid could enable scientists to capitalize on the body’s natural pain-killing pathway without evoking drug tolerance or psychoactivity. Read the paper ...

Researchers are attempting to spread awareness about that condition, cannabinoid hyperemesis syndrome (CHS), and the need for more government oversight in the legal cannabis industry. A rare but ...

These edibles are pushing the boundaries of what consumers expect, offering a discreet and accessible alternative to ...

Agonists of the type 1 cannabinoid receptor (CB1 ... They also activate the β-arrestin signalling pathway, which is associated with side effects and tolerance. Rangari et al.

Cannabis users with type 1 diabetes (T1D) can be misdiagnosed with diabetic gastroparesis on the basis of symptoms or presentation with or without gastric emptying tests; however, cannabinoid ...

VIP36, a new CB1 agonist, targets a cryptic pocket to provide analgesia for chronic pain while minimizing side effects and avoiding opioid-related risks.

Journavx's main ingredient works by targeting a pain-signaling pathway that involves sodium ... He said a synthetic cannabinoid molecule that avoids binding to the high-producing CB1 nerve cell ...

The drug candidate is designed to interact with cannabinoid receptors CB1 and CB2 pathways that have been demonstrated for their role in appetite, metabolism, and energy balance regulation.