Colorectal cancer (CRC) is the third most common malignancy and the second leading cause of cancer-related deaths worldwide.

Cancer associated fibroblasts (CAFs) are a heterogenous group of cells which make up part of the tumor microenvironment ... characterize sub-populations of CAFs and their roles in EMT/Metastasis. Of ...

Major Finding: EMT-associated genomic instability promotes ... Impact: Eliminating cells that display mesenchymal plasticity may slow the progression of pancreatic cancer.

Scientists found that aggressive lung cancer cells create their own electrical network, helping them spread. This unique ...

Now, as a scientist at the University of Pennsylvania, Charly is working to rewrite the future of cancer treatment.

In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

There is a trial of strength at the cellular level. Cells are in constant competition with each other and so eliminate ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

Pancreatic cancer is one of the leading causes of cancer-related mortality, with pancreatic ductal adenocarcinoma (PDAC) ...

Scientists have made an important discovery about the relationship between hematopoietic stem cells (HSCs) and immune response evasion. Their findings show how certain HSCs have regulatory functions ...