Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new ...

The study presented here demonstrates this impairment by successfully identifying a relationship between cancer-associated fibroblasts (CAF) and T cells. The team was required to perform spatial ...

These cells, called cancer-associated fibroblasts (CAF), play an important role in how the cancer develops. Several types of CAF stimulate the growth of cancer cells and contribute to the cancer ...

Since the application of molecular biology in cancer ... Hypoxia causes suppression of anticancer immunity on NSCLC through direct effects on lymphocytes and indirectly by tuning tumor-associated ...

Study Identifies Subtypes of Fibroblasts in Skin Cancer Nov. 19, 2024 — A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes ...

Our research focuses on the tumor-permissive molecular mechanisms underlying cancer-associated fibroblast function as well as immune suppression, and how these stromal mechanisms affect cell fate and ...

Cancer-associated fibroblasts (CAFs) are integral components of the tumor ... This process is predominantly driven by hypoxia within the tumor environment. Under these low-oxygen conditions, cancer ...

Our laboratory previously showed that cancer-associated fibroblasts (CAFs) suppress antitumor immunity in the tumor microenvironment (TME) and that CAF-targeted near-infrared photoimmunotherapy ...

associated with intensified ligand–receptor (LR) communication between cancer and fibroblast cells. Experimentally, we confirmed that endocrine therapy induces the upregulation of compensatory ERBB ...

In one study, both vitamins were associated with fewer complications ... Divergent effects of Vitamin D₃ on human dermal fibroblasts and keratinocytes in wound repair: Implications for ...