Our laboratory previously showed that cancer-associated fibroblasts (CAFs ... T cells in the TME of clinical specimens of esophageal squamous cell carcinoma using immunohistochemistry with a CD45RO ...

This is a useful report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts ... cell types in the stroma using immunohistochemistry techniques on tumor ...

CAFs changes were further examined through HE staining, IHC, and assays for cell viability ... 2015). Within the CRC TME, cancer-associated fibroblasts (CAFs) are particularly prominent among the ...

Using multiplexed immunohistochemistry (FoxP3 ... tumor patterns and TME compositions depending on the primary cancer. Ovarian and gastric cancers were enriched in CD163+ tumor-associated macrophages ...

Despite its importance, research on MTTP in cancer is limited, with no comprehensive pan-cancer studies available. Results: MTTP expression was elevated in at least 1/3 tumors. High expression of MTTP ...

Researchers at Umeå University, Sweden, have discovered a previously unknown type of connective tissue cells that surround ...

Chemokines, our body's chemical messengers, play a crucial role in regulating the immune response.  They are secreted by ...

"The stroma is considered a key component in the aggressive nature of pancreatic cancer, as it interacts with tumor cells, protects them, and hinders the action of drugs. Moreover, stromal cells, ...

Study Identifies Subtypes of Fibroblasts in Skin Cancer Nov. 19, 2024 — A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes ...