The study presented here demonstrates this impairment by successfully identifying a relationship between cancer-associated fibroblasts (CAF) and T cells. The team was required to perform spatial ...

These cells, called cancer-associated fibroblasts (CAF), play an important role in how the cancer develops. Several types of CAF stimulate the growth of cancer cells and contribute to the cancer ...

The study focused on fibroblasts, cells that comprise connective tissue and secrete collagen. One subtype of fibroblasts, cancer-associated fibroblasts (CAFs), play a pivotal role in promoting tumor ...

Cancer-associated fibroblasts (CAFs) are crucial in melanoma metastasis, influencing tumor microenvironments and patient outcomes, especially in immunotherapy contexts. Single-cell RNA sequencing ...

A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment.

Cancer-associated fibroblasts (CAFs) are an important component in solid tumors. They play a decisive role in cancer development and have a significant influence on the success of therapy.

A new study reviews how cancer-associated fibroblasts (CAFs) influence lymph node metastasis. Researchers identified various CAF subsets that interact with the tumor microenvironment, promoting ...

Examination of resistance to nivolumab monotherapy through single-cell analysis of tumors from patients enrolled in the HCRN GU16-260 study of nivolumab monotherapy. This is an ASCO Meeting Abstract ...

While the connection between SASP and cancer development has been known for some time, “SASP is heterogenous, cell-specific and inducer-specific, and the precise senescence profile of colon ...

A new editorial perspective titled "Cancer-associated fibroblasts: challenges and opportunities" has been published in Oncotarget. Cancer-associated fibroblasts (CAFs) are a type of cell that ...

Cancer-associated fibroblasts (CAFs) get a bad rap. The protective, gel-like complex surrounding tumors have been thought to be a no-go for drugs and are known to enforce treatment resistance.