In hypercholesterolemic nephropathy, calpain-1/nAChRα1 in KTRMs activates the TGF-β1/Sp1/Smad signaling pathway to induce fibroblast activation. In cisplatin-mediated renal injury, renal tubular ...

Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with difficult-to-treat epilepsy. In the affected areas, nerve cells and their layer ...

The global burden of chronic kidney disease (CKD) is rising, with more than 800 million people affected worldwide. Vascular ...

Altered dopamine signaling pathways are implicated in epileptic seizures associated with focal cortical dysplasia (FCD) type 2. This condition features atypical neuronal arrangements, complicating ...

Scientists develop lab-grown model of the human sensory pathway to investigate how pain signals are transmitted to the brain.

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This ...

Defense Secretary Pete Hegseth allegedly shared attack plans in a Signal chat including his wife, brother and personal lawyer, The New York Times reported Sunday, citing four people familiar with ...

By Greg JaffeEric Schmitt and Maggie Haberman Defense Secretary Pete Hegseth shared detailed information about forthcoming strikes in Yemen on March 15 in a private Signal group chat that included ...