Community leaders, historians, and visitors from across the region gathered in Cairo this weekend for a Confluences ...

A southern Illinois organization uses family fun and health care to support one underserved Heartland community ...

Years later, in 1869, Grant became a U.S. president like his former Commander-in-Chief Lincoln had done, setting a precedent ...

Marcy’s Shoes rebrands and relocates, Rhodes 101 Stop treats dogs at drive-throughs, hospital construction leads to flooding, ...

Officials say Arab mediators are working on a proposal to end the Israel-Hamas war that would include a five to seven year truce and the release of all remaining hostages.

Click here to view this video from wpsdlocal6.com.

Click here to view this video from wpsdlocal6.com.

The main Palestinian rescue service in Gaza has condemned Israel’s probe into the killings of 15 medical workers last month, calling it a “fabricated investigation.” The army announced the results ...

Cape Girardeau hosted the Fort Wayne Daisies and Muskegon Lassies from the All-American Girls Professional Baseball League ...

The Mississippi River is on track to crest on April 24 at 1 a.m. at a stage of 54.5 feet, which is 6.5 feet above the 48-foot ...

Aerial footage shows severe flooding across the border of Cairo, Illinois, and Wickliffe, Kentucky, on, April 15. The filmer ...

This aerial video shows flooded areas around Cairo, Illinois, and Wickliffe, Kentucky, along Mississippi River on Tuesday, April 15, after relentless rain. RESTRICTIONS AND USAGE TERMS: Please credit ...