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Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice
Familial prion diseases are due to dominantly inherited, germline mutations in the PRNP gene that encodes the prion protein (PrP). The cellular mechanism underlying the pathogenic effect of these ...
Abstract: Protein-Protein Interaction (PPI) networks are believed to be important sources of information related to biological processes and complex metabolic functions of the cell. Identifying ...
Figure 1: FACS analysis of spleen cells from BM-grafted uninfected mice, stained with PrP-specific antibody (open histograms) or unstained (shaded histograms). Figure 2: Confocal analysis of ...
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