Expanding CRISPR's Potential Since its discovery, CRISPR (“Clustered Regularly Interspaced Short Palindromic Repeats”), which ...

Finally, some problems in CRISPR/Cas9 technology have been proposed ... the crRNP identifies invading DNA by small guide RNA (sgRNA) (crRNA:tracrRNA), and Cas protein cut the foreign DNA, thereby ...

Pre-complexed crRNA and tracrRNA (550 pmol) were mixed with purified Cas9 (360 pmol), diluted with PBS to a total volume of 25 µl and incubated for 15 min at room temperature to form ribonucloprotein ...

Pro Bowl quarterback Joe Burrow has made it crystal clear how he wants the Cincinnati Bengals to approach this offseason. Do whatever it takes to ensure that wide receiver Ja'Marr Chase, edge ...

Tennis fans are naturally interested in the world's top-ranked players. However, fans and media members cannot get enough from WTA World No. 2 Iga Swiatek. The Polish superstar is always asked ...

From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or ...

The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it ...

Lipoprotein(a), or Lp(a), is a protein that transports cholesterol in the blood. High levels of Lp(a) in the blood can increase the likelihood of plaques or blood clots forming in the arteries. As ...

The study by Pudlowski et al. shows that a previously-identified protein complex, composed of delta- and epsilon-tubulin together with TEDC1 and TEDC2, functions in generating centriolar triplet ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Control of gene expression is commonly ...