A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing.

This study “harnesses CRISPR pooled screening technology to help us figure out where the functional regions in the noncoding genome [are],” he explained. Gersbach and colleagues created lentiviral ...

Besides harnessing endogenous CRISPR-Cas systems to engineer human-associated microbes ... highlighting the approach’s potential to screen for bacteria amenable to genome editing without the need to ...

Bioengineering professor and The Grainger College of Engineering's Dean, Rashid Bashir, led a team of researchers in a ...

Yet others, called base editors, change one letter of the DNA code to another. So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to ...

Researchers have been working to find CRISPR/Cas nucleases with greater specificity ... a GFP activation expression reporting system to screen 13 Cas12b nucleases. Interestingly, one of them ...

The blueprints for these molecules can be found in the ... CRISPR-Cas Technology: Balancing Efficiency and Safety Dec. 4, 2024 — Researchers have uncovered a serious side effect of using the ...

Expanding CRISPR's Potential Since its discovery, CRISPR (“Clustered Regularly Interspaced Short Palindromic Repeats”), which ...

CRISPR/Cas experiments are continually increasing ... To put it in numbers: with their previous vector, a CRISPR screen looking for all double knockouts of just 20 genes was estimated to require ...