CRISPR-Cas9 is a powerful gene editing system that has revolutionized our ability to treat disease and probe the human genome. CRISPR has been used to edit the genomes of animals, plants, and microbes ...

A CRISPR treatment seems to have been effective for a baby’s devastating disease, but it is not clear whether such bespoke ...

At the upcoming annual meeting of the American Society of Gene and Cell Therapy, scientists from Huidagene Therapeutics will share an update on the development of their CRISPR-high-fidelity(hf ...

Using CRISPR gene editing ... plaques that build up in the brains of Alzheimer’s patients. In the brains of mice, the engineered cells were found to preserve neurons, decrease inflammation ...

We expect investors to focus on the sales numbers of CRISPR Therapeutics’ CRSP sole-marketed product, Casgevy, and other pipeline updates when it reports first-quarter 2025 results. The Zacks ...

In new mouse models of the disease ... To fix the dysferlin mutation, Escobar uses CRISPR-Cas9, which is often described as "gene-editing scissors" and for which a Nobel Prize was awarded in ...

After CRISPR editing, APP stays on the cell surface ... Cutting off APP’s last exon countered disease phenotypes in the APP-KI mice. Enlarged lysosomes, microgliosis and astrocytosis, and synaptic ...

It’s been a monumental year for Crispr, the molecular tool scientists use to edit genetic material. This November, the United Kingdom authorized the first medical treatment using Crispr gene ...

Vertex Pharmaceuticals plans to sell a gene-editing treatment for sickle-cell disease. A patent on CRISPR could stand in the way. That’s a real nice CRISPR cure you have there. It would be a ...

The decision by an advisory committee may lead to Food and Drug Administration approval of the first treatment for humans that uses the CRISPR gene-editing system. By Gina Kolata Gina Kolata has ...

A ERK5 S496A (dephosphorylation mimic) knock in (KI) mouse model was generated using CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short ...