A CRISPR treatment seems to have been effective for a baby’s devastating disease, but it is not clear whether such bespoke ...

At the upcoming annual meeting of the American Society of Gene and Cell Therapy, scientists from Huidagene Therapeutics will share an update on the development of their CRISPR-high-fidelity(hf ...

Col-WT and Col-KI mice were treated with doxycycline for ten days and six weeks, respectively. Here, doxycycline treatment was initiated several days before the onset of severe cachexia, so that ...

In a brand new study carried out with research colleagues in Switzerland, Klas Blomgren can show that another cell death mechanism, autophagy, is activated in both mice and children who ...

Ed Silverman, a senior writer and Pharmalot columnist at STAT, has been covering the pharmaceutical industry for nearly three decades. He is also the author of the morning Pharmalittle newsletter ...

Using CRISPR gene editing ... plaques that build up in the brains of Alzheimer’s patients. In the brains of mice, the engineered cells were found to preserve neurons, decrease inflammation ...

This study presents and characterizes a Dnmt3a mutant mouse model which carries a heterozygous hotspot R878H mutation frequently found in human cancers, providing insights into Dnmt3a-mutant ...