As a postdoc, Komor found a way to achieve gene-editing with higher efficiencies and a lower incidence of indels by avoiding ...

New CRISPR alternative can 'install' whole genes, paving the way to treatment for many genetic disorders Man gets sperm-making stem cell transplant in first-of-its-kind procedure ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders ...

Collaborating with CRISPR-Cas9 co-inventor Jennifer Doudna and Jill ... Successful editing produced a clear visual marker—affected areas turned white, including seedlings, confirming the edits ...

Nexiguran ziclumeran (nex-z) is an investigational therapy based on CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and associated Cas9 endonuclease) targeting the gene ...

optimized several parameters for single cell culturing and established an automated workflow for CRISPR/Cas9-based genome editing. When validated with a variety of genetic backgrounds and target genes ...

Here, we systematically profiled the factors that regulate protein stability of wild-type and mutant p53 using marker-based genome-wide CRISPR ... FVBN background, a generous gift of Sean Egan, The ...

Scientists from Zhejiang University have developed a novel delivery vehicle for CRISPR-Cas9 that is more effective than lipid nanoparticles (LNPs) in treating lung cancer. Rapid liquid nitrogen ...

To date, no standardized protocols exist to transfect RNPs to soybean protoplasts through electroporation with reasonable mutation efficiency, which would greatly facilitate the CRISPR/Cas9 system to ...

The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease. However, the CRISPR/Cas9 ...

broad-host-range CRISPR-Cas9 delivery tool. Please introduce yourself, tell us about your career background, and provide insight into what has inspired your career to date? Hiya! My name is David ...

CRISPR-Cas9 gene editing technology is widely used to to help study genes of interest and modify disease-associated genes. However, the system is associated with adverse effects, including ...