CRISPRware is a new tool scientists can use to design the best guide RNAs to edit genes in many organisms, without the need for deep bioinformatics expertise. By making gene editing more precise and ...

Personalized CRISPR cures for children born with rare genetic diseases are now a step closer to being more widely available.

This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least ...

In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

In this interview, Professor James J. Collins, founder of the field of Synthetic Biology, discusses his journey to founding ...

Image Credit: ChatGPT This discovery fills a critical knowledge ... The tsl gene discovery also facilitates the use of ...

Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about ...

New research has found a novel target with therapeutic potential for metastatic eye melanoma—an aggressive eye cancer—with ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence.

Scalable modulation of CRISPR‒Cas enzyme activity using photocleavable phosphorothioate DNA CRISPR systems are powerful tools for gene editing and diagnostics, but their regulation is challenging.