Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...

The agreement grants Jumpcode access to ERS' CRISPR/Cas9 patent portfolio ... we are poised to drive breakthroughs in basic research, infectious disease detection, molecular diagnostics, and ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

By inserting an entire gene, the tool offers a one-and-done approach that overcomes hurdles from CRISPR gene editing ... "By studying basic biology in our cells, we can find inspiration for ...

In this study, we demonstrated the exploitation of CRISPR/Cas9 as a high precision system for editing the composition and function of eECMs. Human mesenchymal stromal/stem cell (hMSC) lines were ...

Apr. 15, 2025 — Wildflowers growing on land previously used for buildings and factories can accumulate lead, arsenic and other metal contaminants from the soil, which are consumed by pollinators ...

To understand the mechanism of gene editing using the CRISPR/Cas9 technology, it is essential to understand the basic mechanism of action of this system. The acquisition machinery (Cas enzymes) ...