The incorporation of CRISPR/Cas9 into clinical settings has promising applications for the future treatment of genetic disorders, human immunodeficiency virus (HIV) infection, and various ...

Scientists program CRISPR-Cas9 to introduce blunt end double-strand DNA breaks at target genomic loci based on nearby protospacer adjacent motifs (PAMs) and engineered target-specific single guide ...

CRISPR-Cas9 gene editing technology is widely used to to help study genes of interest and modify disease-associated genes. However, the system is associated with adverse effects, including ...

Discover how CRISPR-Cas9 technology is revolutionizing spider silk production with red fluorescent fibers and advancing genetic research.

CRISPR gene editing means a cure for sickle cell disease is on the horizon. However, the life-changing treatment is likely to remain out of reach for most of those who could benefit.

CRISPRware is a new tool scientists can use to design the best guide RNAs to edit genes in many organisms, without the need for deep bioinformatics expertise. By making gene editing more precise and ...

Researchers are working to reveal potential threats to the efficacy of CRISPR/Cas9 gene editing, even when it appears to be working as planned.

In research published in Nature Catalysis, scientists at Florida State University produced the first high-resolution, time-lapsed images showing magnesium ions interacting with the CRISPR-Cas9 ...

The divergence between the positions of the appeals court and the PTAB centers on the importance of early uncertainty about whether CRISPR-Cas9 editing would work in eukaryotic cells.

Plant scientists are using CRISPR-Cas9 to engineer new lines of crop plants, including the oilseed crop camelina shown here, that grow well in an environment altered by climate change.

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders ...