Dsc2 KO and knock-in (KI) mouse models were generated using CRISPR/Cas9 technology on a C57BL/6J genetic background. Dsc2 KO mice were generated by deleting exon 4. KI mice were created by inserting ...

A federal appeals court said the patent office made legal errors in awarding foundational patents for CRISPR-Cas9 to the ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 ...

Researchers at Tel Aviv University have announced that they have successfully removed half of a tumor in a mouse's head using ... Aviv University was to use CRISPR-Cas9 to remove the protein ...

Researchers at Novartis BioMedical Research in the US and Switzerland have identified a molecular target that may provide a ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants ... have developed a machine learning model that permits the prediction of bespoke Cas9 proteins that are more ...

Now, by introducing the Icelandic mutation into an Alzheimer's disease mouse model that lacked the Swedish mutation, a team led by Hiroki Sasaguri of the RIKEN Center for Brain Science has shown ...

The medical promise of CRISPR gene editing can be seen most easily in current research on oral cancer, which affects more than 50,000 Americans every year. An increasing challenge in the treatment ...

A new model mouse for the neurodegenerative disorder has helped uncover the protective mechanism of a genetic mutation Figure 1: A micrograph showing inflammatory responses in the cortex of the new ...

Is your mouse suddenly registering two clicks even though you swear you’re only clicking once? One of the most common causes of that is wear and tear. But before you zip out and buy a new mouse ...