Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
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CRISPR-Cas9 Off-Target Effects: Challenges and SolutionsThe CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
Researchers find a master epigenetic switch that activates silenced genes to compensate for their missing counterparts in a ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and possible regeneration.
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