We provide transgene expression in mammalian cell lines using lentiviral and retroviral transduction and gene knockout and knockin using CRISPR/Cas9 technologies. 1. STABLE CELL LINE GENERATION ...

CRISPR interference (CRISPRi ... directs the complex to the DNA target site. Horizon offers lentiviral and transient approaches for both repressor protein and guide introduction. The native Cas9 ...

A powerful new CRISPR/Cas9 tool can be used to produce homozygous mutations within a generation, but scientists call for caution. “The study is well done and also very elegant,” said Ji-Long Liu of ...

CRISPR-Cas9 based gene editing is a powerful tool which can induce ... bio-informatic processing and analysis requirements while using CRISPR. This CRISPR vector system has been applied in many crops ...

One of the barriers to using CRISPR-Cas9 gene editing in the clinic is the possibility that the enzyme will clip DNA in the wrong spot. In a study published in Nature today (September 12), researchers ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

The agreement grants Jumpcode access to ERS' CRISPR/Cas9 patent portfolio, empowering the company to advance the sensitivity and efficiency of next-generation sequencing (NGS) and expand ...